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Dyadic is issued two new U.S. patents

Date: 2011-04-08 08:53:05.0
Author: Dyadic International, Inc.

FungusJUPITER, Fla. - Dyadic International, Inc. ("Dyadic"), a global biotechnology company focused on the discovery, development, manufacture and sale of enzyme and protein products for the bioenergy, industrial enzyme and biopharmaceutical industries, has announced that it has been issued U.S. Patent No. 7,906,309 entitled, “Expression-Regulating Sequences and Expression Products in the Field of Filamentous Fungi” and U.S. Patent No. 7,892,812 entitled, “Chrysosporium Cellulase and Methods of Use” by the United States Patent and Trademark Office (“USPTO”).
U.S. Patent No. 7,906,309  - “Expression-Regulating Sequences and Expression Products in the Field of Filamentous Fungi”

The inventions embodied by this patent are genes and their corresponding enzymes from glycosyl hydrolase family 10 having xylanase activity which are derived from Chysosporium fungal strains. Other related applications claim cellobiohydrolases and glyceraldehyde phosphate dehydrogenases. These enzymes have proven to be effective in breaking down the major component of plant cell walls, commonly known as lignocellulosic biomass, into fermentable C5 sugars which can be used in the production of biofuels and biochemicals. These genes and enzymes were isolated from Dyadic’s patented and proprietary C1 fungus and identified through the genome annotation project conducted by Dyadic in conjunction with Scripps Florida.

Dyadic’s President and Chief Executive Officer, Mark Emalfarb, stated, “This patent protects Dyadic’s ability to use its C1 technology to make fermentable C5 sugars in addition to the C6 sugars allowed by our previously awarded biofuels patent.”

U.S. Patent No. 7,892,812 - “Chrysosporium Cellulase and Methods of Use”

The inventions embodied by this patent are industrial uses and novel methods of manufacturing endoglucanases and other groups of neutral or alkaline cellulases that are isolated from Chrysosporium fungal strains. These enzymes work over broader temperature and pH ranges than other commercially available enzymes. Endoglucanases are commercially useful in the processing of cellulose-based materials with applications in the biofuels, biochemicals, beverage, feed, textiles and pulp and paper industries among other potential uses.

These patents are the eighth and ninth U.S. patents issued to Dyadic adding to its portfolio of 74 international patents and more than 33 pending patent applications worldwide which cover various features of Dyadic’s proprietary technologies.

About Dyadic

Dyadic International, Inc. is a global biotechnology company that uses its patented and proprietary technologies to conduct research, development and commercial activities for the discovery, development, manufacture and sale of enzyme and protein products for the bioenergy, industrial enzyme and biopharmaceutical industries.

Dyadic utilizes an integrated technology platform based on its patented and proprietary C1 fungus, which enables the development and large scale manufacture of low cost proteins and enzymes for diverse market opportunities. The C1 Platform Technology can also be used to screen for the discovery of novel genes and proteins. Dyadic actively pursues licensing arrangements and other commercial opportunities to leverage the value of these technologies by providing its partners and collaborators with the benefits of manufacturing and/or utilizing the enzymes which these technologies help produce.


These newly issued patents are accessible on the USPTO’s website here or on Dyadic’s website here


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